Cleanance Comedomed, our best global acne solution and an innovation from the Laboratoires Dermatologiques Avène, has shown proven clinical effectiveness from seven days*, fights the appearance of spots from the root with a unique action and prevents them from reappearing. Expert care for oily, acne-prone skin, Cleanance Comedomed is formulated using Comedoclastin™, a plant extract from the seeds of Milk thistle. This active ingredient with patented properties** directly targets micro imperfections, reduces the appearance of existing spots and blackheads and prevents new imperfections from appearing.

Cleanance Comedomed, applied twice a day, reduces imperfections within seven days* and provides clinically proven anti-recurrence action, during 1 year***. Can be used by adults and teenagers from the age of 12. Non-comedogenic, high-tolerance* for acne-prone skin, its fast-absorbing, non-greasy texture leaves skin mattified. Cleanance Comedomed can be used alone, with other products, or after acne medication.